收藏本站
收藏 | 手机打开
二维码
手机客户端打开本文

Stimulating Extracellular Vesicles Production from Engineered Tissues by Mechanical Forces

Shaowei Guo  Lior Debbi  Barak Zohar  Roee Samuel  Roni S.Arzi  Adina I.Fried  Tahel Carmon  Dudi Shevach  Idan Redenski  Inbar Schlachet  Alejandro Sosnik  Shulamit Levenberg  
【摘要】:正Background: Extracellular vesicles (EVs) have emerged as a promising strategy to promote tissue regeneration. However, overcoming the low EV production yield remains a big challenge in translating EV-based therapies to the clinical practice. Current EV production relies heavily on 2D cell culture, which is not only less physiologically relevant to cells, but also requires substantial medium and space. Therefore, we aimed to boost EVs secretion by a novel method combining tissue engineering and biomechanics.

知网文化
【相似文献】
中国期刊全文数据库 前20条
1 Sigrun Lange;;Peptidylarginine deiminases and extracellular vesicles:prospective drug targets and biomarkers in central nervous system diseases and repair[J];Neural Regeneration Research;2021年05期
2 Quoc-Viet Le;Jaiwoo Lee;Hobin Lee;Gayong Shim;Yu-Kyoung Oh;;Cell membrane-derived vesicles for delivery of therapeutic agents[J];Acta Pharmaceutica Sinica B;2021年08期
3 Yan Zhao;Xiaolu Li;Wenbo Zhang;Lanlan Yu;Yang Wang;Zhun Deng;Mingwei Liu;Shanshan Mo;Ruonan Wang;Jinming Zhao;Shuli Liu;Yun Hao;Xiangdong Wang;Tianjiao Ji;Luo Zhang;Chenxuan Wang;;Trends in the biological functions and medical applications of extracellular vesicles and analogues[J];Acta Pharmaceutica Sinica B;2021年08期
4 Hongen Cao;Ruonan Ma;Sainan Chu;Juqun Xi;Lei Yu;Rong Guo;;Synergistic effect of T80/B30 vesicles and T80/PN320 mixed micelles with Se/C on nasal mucosal immunity[J];Chinese Chemical Letters;2021年09期
5 Alisa A.Shaimardanova;Valeriya V Solovyeva;Daria S.Chulpanova;Victoria James;Kristina V Kitaeva;Albert A.Rizvanov;;Extracellular vesicles in the diagnosis and treatment of central nervous system diseases[J];Neural Regeneration Research;2020年04期
6 Yi Xian;Mengxuan Zhou;Shangchen Han;Rong Yang;Yi Wang;;A FRET biosensor reveals free zinc deficiency in diabetic beta-cell vesicles[J];Chinese Chemical Letters;2020年02期
7 Bo Yu;Xiao-Rong Li;Xiao-Min Zhang;;Mesenchymal stem cell-derived extracellular vesicles as a new therapeutic strategy for ocular diseases[J];World Journal of Stem Cells;2020年03期
8 Hui Xie;Kaili Di;Rongrong Huang;Adeel Khan;Yanyan Xia;Hongpan Xu;Chang Liu;Tingting Tan;Xinyu Tian;Han Shen;Nongyue He;Zhiyang Li;;Extracellular vesicles based electrochemical biosensors for detection of cancer cells:A review[J];Chinese Chemical Letters;2020年07期
9 Gabriella Pocsfalvi;Christopher Stanly;Annalisa Vilasi;Immacolata Fiume;Rosarita Tatè;Giovambattista Capasso;;Employing extracellular vesicles for non-invasive renal monitoring:A captivating prospect[J];World Journal of Clinical Urology;2014年02期
10 ;Liquid crystal model of vesicles under electromechanical fields[J];医用生物力学;2010年S1期
11 ;Morphological stability analysis of vesicles with mechanical-electrical coupling effects[J];Acta Mechanica Sinica;2010年01期
12 ;Characterization of GLUT4-containing vesicles in 3T3-L1 adipocytes by total internal reflection fluorescence microscopy[J];Science in China(Series C:Life Sciences);2009年07期
13 胡坤生 ,王敖金 ,lanE.G.Morrison ,RichardJ.Cherry;Electron microscopic observation and rotational diffusion measurement of bacteriorhodopsin in lipid vesicles[J];Science in China(Series B);2001年06期
14 Anna Picca;Flora Guerra;Riccardo Calvani;Hélio José Coelho-Junior;Cecilia Bucci;Emanuele Marzetti;;Circulating extracellular vesicles:friends and foes in neurodegeneration[J];Neural Regeneration Research;2022年03期
15 Zhi Yan;Hua Wang;Lan Mu;Zhi-De Hu;Wen-Qi Zheng;;Regulatory roles of extracellular vesicles in immune responses against Mycobacterium tuberculosis infection[J];World Journal of Clinical Cases;2021年25期
16 Cristina Agliardi;Mario Clerici;;Blood extracellular vesicles (EVs) of central nervous system origin: a window into the brain[J];Neural Regeneration Research;2020年01期
17 Yun-Long Han;Ming-Ming Ding;Rui Li;Tong-Fei Shi;;Kinematics of Non-axially Positioned Vesicles through a Pore[J];Chinese Journal of Polymer Science;2020年07期
18 Hui Chen;Min-Hui Li;;Recent Progress in Fluorescent Vesicles with Aggregation-induced Emission[J];Chinese Journal of Polymer Science;2019年04期
19 Laura Morán;Francisco Javier Cubero;;Extracellular vesicles in liver disease and beyond[J];World Journal of Gastroenterology;2018年40期
20 Zhihan Zhu;Bikram Shah Kalyan;Lukui Chen;;Therapeutic potential role of exosomes for ischemic stroke[J];Brain Science Advances;2019年02期
中国重要会议论文全文数据库 前20条
1 Shaowei Guo;Lior Debbi;Barak Zohar;Roee Samuel;Roni S.Arzi;Adina I.Fried;Tahel Carmon;Dudi Shevach;Idan Redenski;Inbar Schlachet;Alejandro Sosnik;Shulamit Levenberg;;Stimulating Extracellular Vesicles Production from Engineered Tissues by Mechanical Forces[A];2021海峡两岸暨港澳精准医学青年博士论坛论文集[C];2021年
2 Lan Chen;Chenxi Hou;Jingli Ren;Yuxin Pei;Jiafeng Xi;Yijie Hua;Yuchen Lu;Zhichao Pei;;A multifunctional supramolecular vesicle based on complex of cystamine dihydrochloride capped pillar[5]arene and galactose derivative for targeted drug delivery[A];中国化学会第三届全国糖化学会议会议手册[C];2019年
3 Yan Zhou;Shaobin Miao;Dongsheng Deng;Weilong Wu;Guohui Kang;Baoming Ji;;Reversibly Photoswitchable Dual-Color Fluorescent Based on Crown Ether[A];全国第十九届大环化学暨第十一届超分子化学学术讨论会摘要论文集[C];2018年
4 Honglin Jia;Shinuo Cao;Heming Chen;Jiawen Fu;Juan Yang;Jun Zheng;;Maturation and function of endomembrane systems of T.gondii[A];中国畜牧兽医学会兽医寄生虫学分会第一届青年科学家学术论坛摘要集[C];2019年
5 章丹;Xianya Qin;Tingting Wu;Qi Qiao;Zhiping Zhang;;Self-growth of gold nanostructures based on cell and cell vesicles for combinatorial therapy against tumor[A];2018年第十二届中国药物制剂大会论文集[C];2018年
6 Kaiyao Huang;Huan Long;Christopher RWood;Dennis Diener;Stephen Geimer;Joel Rosenbaum;;Ectosome-like vesicles released from the cilium/flagellum carry specific biologically-active proteins[A];细胞—生命的基础——中国细胞生物学学会2013年全国学术大会·武汉论文摘要集[C];2013年
7 ;Electromechanical liquid crystal theory of vesicles[A];第九届全国生物力学学术会议论文汇编[C];2009年
8 Xudong Liang;Yan Zu;Yan-Ping Cao;Chun Yang;;A dual-scale model for the caveolin-mediated vesiculation[A];第一届国际暨第十三次中国生物物理学术大会摘要集——S8膜蛋白结构与功能、S9生物膜的动态变化与功能[C];2013年
9 俞立;;Migrasome and migracytosis[A];中国生物化学与分子生物学会2016年全国学术会议论文集[C];2016年
10 Richard W.Tsien;N.Charles Harata;T Thiagarajan;M.Lindskog;J.Kim;;Probing the power of central nerve terminals at the level of single vesicles and single transmission events[A];Proceedings of the 7th Biennial Meeting and the 5th Congress of the Chinese Society for Neuroscience[C];2007年
11 Stefan Albert;Serguei E. Tcheperegine;Christopher G. Burd;Dieter Gallwitz;;The GAP activity of Msb3p and Msb4p for the Rab GTPase Sec4p is required for efficient exocytosis and actin organization[A];2006年度学术研讨会论文摘要汇编[C];2006年
12 罗振革;;Membrane dynamics in axonal growth and pruning[A];细胞—生命的基础——中国细胞生物学学会2013年全国学术大会·武汉论文摘要集[C];2013年
13 Shanwei Li;Huaijian Dong;Weike Pei;Chaonan Liu;Sha Zhang;Tiantian Sun;Xiuhua Xue;Haiyun Ren;;Ll FH1-mediated interaction between actin fringe and exocytic vesicles is involved in pollen tube tip growth[A];2016年全国植物生物学大会摘要集[C];2016年
14 Seunghoon LEE;Kyongmin KIM;Zhimin J.ZHOU;;Differential control of ACh and GABA corelease from a single retinal neuron[A];Proceedings of the 7th Biennial Meeting and the 5th Congress of the Chinese Society for Neuroscience[C];2007年
15 Zeming Wu;Hongyan Yuan;Xinyun Zhang;Xin Yi;;Sidewall contact regulating the nanorod packing inside vesicles with relative volumes[A];中国力学大会论文集(CCTAM 2019)[C];2019年
16 Xiaoying Zhou;Yazhou Cui;Jing Luan;Xiaoyan Zhou;Genglin Zhang;Xiumei Zhang;Jinxiang Han;;Label-free quantification proteomics reveals novel calcium binding proteins in matrix vesicles isolated from mineralizing Saos-2 cells[A];第八届全国医学生物化学与分子生物学第五届全国临床应用生物化学与分子生物学2013华东六省一市生物化学与分子生物学联合学术研讨会论文汇编[C];2013年
17 Liang Jiang;Yazhou Cui;Jing Luan;Xiaoyan Zhou;Xiaoying Zhou;Jinxiang Han;;A comparative proteomics study on matrix vesicles of osteoblast-like Saos-2 and U2-OS cells[A];第八届全国医学生物化学与分子生物学第五届全国临床应用生物化学与分子生物学2013华东六省一市生物化学与分子生物学联合学术研讨会论文汇编[C];2013年
18 Guang-Ming GAN;Wei XIE;;Morphological identification and development of neurite in drosophila ventral nerve cord neuropile[A];中国神经科学学会第十届全国学术会议论文摘要集[C];2013年
19 隋森芳;;胞间囊泡运输与疾病[A];生物膜与重大疾病学术研讨会论文集[C];2004年
20 Panhong Liang;Li Mao;Yanping Li;Shaohua Zhang;Xiaola Guo;Guangxue Liu;Lijie Wang;Junling Hou;Yadong Zheng;Xuenong Luo;;Identification and molecular characterization of exosome-like vesicles derived from Taenia asiatica adult worms[A];第十一届全国寄生虫学青年工作者学术研讨会摘要集[C];2018年
中国博士雷竞技下载ios 全文数据库 前4条
1 Ghellab Salah Eddine;基于磷脂组装体的生物膜及杂化生物材料的制备[D];哈尔滨工业大学;2020年
2 高美华;十二烷基磷酸钠和其苯磺酸溶液聚集行为研究[D];山东大学;2021年
3 林思浩;间充质干细胞的细胞外囊泡减轻小鼠缺血再灌注肾损伤的相关研究[D];上海交通大学;2019年
4 白丽;囊泡转运步骤的分辨及其调控机制研究[D];华中科技大学;2006年
中国硕士雷竞技下载ios 全文数据库 前3条
1 洪佳丹;脂质囊泡稳定性及其介导的磷酸钙矿化过程初步研究[D];华南理工大学;2019年
2 解晓倩;Desulfovibrio fairfieldensis分泌微囊泡的生物学特征及在肝纤维化发生发展中的作用[D];江南大学;2021年
3 王新城;巨型正反相蛋黄卵磷脂囊泡的制备与表征[D];天津大学;2015年
 快捷付款方式  订购知网充值卡  订购热线  帮助中心
  • 400-819-9993
  • 010-62982499
  • 010-62783978